14.  Gaínza Lein M; Sánchez Fernández I; Jackson M; Abend, NS, Arya; Brenton JN, Carpenter JL, Chapman KE, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Kapur K, Mikati MA. Peariso K, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright, MS, Wilfong, AA, Williams K, Loddenkemper T, on behalf of Pediatric Status Epilepticus Research Group (pSERG).  Time to treatment and Outcome in Pediatric Refractory Status Epilepticus.  Poster presentation at the American Epilepsy Society Meeting, Houston, 2016. 

1. Loddenkemper T, Sánchez Fernández I, Abend N, Agadi S, Carpenter J, Chapman K, Gaillard W, Goodkin H, Hahn C, Mikati M, Peariso K, Ramgopal S, Arya R, Ream M, Riviello J, Veerapandiyan A, Williams K, Glauser T. Pediatric status epilepticus research group (pSERG): Establishment of a Multicenter North American Research Network. Poster presentation at the American Epilepsy Society Meeting 2012. 


12.  Arya R, Peariso K, Gaínza Lein M, Harvey J, Brenton JN, Goodkin HP, Mikati MA, Sánchez Fernández I, Stosic M, Tchapyjnikov D, Wilfong AA, Glauser TA, Loddenkemper T, And the Pediatric Status Epilepticus Research Group (pSERG).  Efficacy and Safety of Ketogenic Diet for Management of Refractory Status Epilepticus.  Poster presentation at the American Epilepsy Society Meeting, Houston, 2016. 

2. Loddenkemper T, Abend N, Agadi S, An S, Arya R, Carpenter J, Chapman K, Gaillard W, Glauser T, Goodkin H, Mikati M, Peariso K, Ream M, Sánchez Fernández I, Tasker R, for pSERG. Management of pediatric refractory convulsive status epilepticus in clinical practice. Pediatric status epilepticus research group (pSERG). Poster presentation at the American Epilepsy Society Meeting 2013. 


​​Abstracts

Manuscripts

1. Sánchez Fernández I, Abend NS, Agadi S, An S, Arya R, Carpenter JL, Chapman KE, Gaillard WD, Glauser TA, Goldstein D, Goldstein JL, Goodkin HP, Hahn CD, Heinzen EL, Mikati MA, Peariso K, Pestian JP, Ream M, Riviello JJ, Tasker RC, Williams K, Loddenkemper T. Gaps and opportunities in refractory status epilepticus research in children: A multi-center approach by the Pediatric Status Epilepticus Research Group (pSERG). Seizure. 2014;23(2):87-9.

 


​2. Sánchez Fernández I, Abend, NS Agadi S, An S, Arya R, Brenton JN, Carpenter JL, Chapman KE, Gaillard WD, Glauser TA, Goodkin HP, Kapur K, Mikati MA, Peariso K, Ream M, Riviello Jr J, Tasker RC, Loddenkemper T, on behalf of the Pediatric Status Epilepticus Research Group (pSERG). Time from Convulsive Status Epilepticus Onset to Anticonvulsant Administration in Children. Neurology. 2015;84(23):2304-2311.



3. Tasker RC, Goodkin HP, Sánchez Fernández I, Chapman KE, Abend NS, Arya R, Brenton JN, Carpenter JL, Gaillard WD, Glauser TA, Goldstein J, Helseth AR, Jackson MC, Kapur K, Mikati MA, Peariso K, Wainwright MS, Wilfong AA, Williams K, Loddenkemper T, on behalf of the Pediatric Status Epilepticus Research Group (pSERG).  Refractory Status Epilepticus in Children: intention-to-treat with continuous infusions of midazolam and pentobarbital.  Pediatric Critical Care Medicine. 2016.​



4. Sánchez Fernández I, Jackson MC, Abend NS, Arya R, Brenton JN, Carpenter JL, Chapman KE, Gaillard WD, Gaínza-Lein M, Glauser TA, Goldstein J, Goodkin HP, Helseth AR, Kapur K, McDonough T, Mikati MA, Peariso K, Riviello Jr J, Tasker RC, Topjian A, Wainwright MS, Wilfong AA, Williams K, and Loddenkemper T, on behalf of the Pediatric Status Epilepticus Group (pSERG). Refractory status epilepticus in children with and without prior epilepsy or status epilepticus. Neurology. 2016. 

​​4. Gaillard WD, Goodkin HP, Abend NS, Agadi S, Arya R, Basu R, Carpenter J, Chapman K, Dean N, Glauser T, Jackson M, Mikati M, Peariso K, Rathore G, Sánchez Fernández I, Tasker RC, Topjian, Turner DA, Wilfong A, Williams K, Loddenkemper T. Etiology of pediatric refractory convulsive status epilepticus. Results from the Pediatric Status Epilepticus Research Group (pSERG). Platform presentation at the 66th American Academy of Neurology. Neurology. 2014;82(10):Supplement S29.005.


​15.  Sansevere, Arnold J. ; Abend, Nicholas S.; Arya, Ravindra; Brenton, J. Nicholas; Carpenter, Jessica L.; Chapman, Kevin E.; Gaillard, William D. ; Gainza Lein, Marina; Glauser, Tracy A.; Goldstein, Joshua; Goodkin, Howard P.; Jackson, Michelle;  Kapur, Kush;  Mikati, Mohamad A.; Payne, Eric T. ; Peariso, Katrina; Riviello J Jr; Sánchez Fernández, Iván; Tasker, Robert C.; Tchapyjnikov, Dmitry; Topjian, Alexis; Wainwright, Mark; Wilfong, Angus; Williams, Korwyn; Loddenkemper, Tobias; And the Pediatric Status Epilepticus Research Group (pSERG). EEG Reporting in the Pediatric Intensive Care Unit.  Poster presentation at the American Epilepsy Society Meeting, Houston, 2016. 

Awards

5. Sánchez Fernández I, Abend NS, Agadi S, Arya R, Basu R, Carpenter J, Chapman K, Dean N, Gaillard WD, Glauser T, Goodkin HP, Jackson M, Mikati M, Peariso K, Rathore G, Tasker RC, Topjian, Turner DA, Wilfong A, Williams K, Loddenkemper T. Where and how are the initial antiepileptic drugs administered to children who develop refractory status epilepticus? Results from the Pediatric Status Epilepticus Research Group (pSERG). Poster presentation at the 66th  American Academy of Neurology. Neurology. 2014;82(10):Supplement S3.006.


11. Gaínza Lein, Marina; Sánchez Fernández, Iván; Jackson, Michele; Abend, Nicholas; Arya, Ravindra; Brenton, J. Nicholas; Carpenter, Jessica L.; Chapman, Kevin; Gaillard, William D.; Glauser, Tracy; Goldstein, Joshua; Goodkin, Howard P.; Helseth, Ashley; Kapur, Kush; Mikati, Mohamad; Peariso, Katrina; Tasker, Robert; Topjian, Alexis; Wainwright, Mark; Wilfong, Angus; Williams, Korwyn; Loddenkemper, Tobias; And the Pediatric Status Epilepticus Research Group (pSERG): Status Epilepticus in Children: First Line Meication and Dosing.  Poster presentation at the American Clinical Neurophysiology Society Meeting 2016. 

1.Title: Outcome in refractory Status epilepticus (PI Loddenkemper)
Funding Agency: Epilepsy Foundation of America (EF-213583)
Dates: 07/01/2011-06/30/2012, no cost extension from 07/01/2012-06/30/2013
This grant supported the establishment of outcome measures across 8 different sites, as well as allowed for set up of a common charter, data sharing agreements, and a centralized electronic data entry form at Cincinnati Children's Hospital Medical Center with the aim to track and identify treatment interventions that may indicate outcome. 
http://www.epilepsyfoundation.org/resources/newsroom/pressreleases/Epilepsy-Foundation-Announces-Research-Grant-Winners.cfm

2. Title: Outcome in Status epilepticus (PI Loddenkemper)
Funding Agency: Program for Patient Safety and Quality, Boston Children's Hospital, MA
Dates: 10/01/2011-09/30/2012
This grant supported the development of benchmarks and outcome markers of frequent seizures and pediatric status epilepticus at Boston Children's Hospital as a grant in aid to the multicenter grant. Measures were subsequently rolled out to the consortium.

3.Title: Pediatric Status Epilepticus Research Group  (PI Loddenkemper)
Funding Agency: American Epilepsy Society & Epilepsy Foundation of America, Infrastucture Award
Dates: 01/01/2013-12/31/2013
The goal of this project is to collect prospective data to determine diagnostic and therapeutic biomarkers in patients with refractory status epileticus. Data collection lead to enrollment of 150 refractory status epilepticus cases at 10 sites. Funding by the AES/EFA infrastructure award ends in December 2014. The current current grant application aims to obtain support that allows us to continue our efforts.
http://www.epilepsyfoundation.org/research/research-infrastructure-grant.cfm
http://www.aesnet.org/research/aes-sponsored-grant/research-infrastructure-awards/research-infrastructure-awards


4. Title: Pediatric Status Epilepticus Research Group  (PI Loddenkemper)
Funding Agency: American Epilepsy Society & Epilepsy Foundation of America, Infrastucture Award
Dates: 01/01/2014-12/31/2014 (competitive renewal)
The goal of this project is to collect prospective data to determine diagnostic and therapeutic biomarkers in patients with refractory status epileticus. Data collection lead to enrollment of 150 refractory status epilepticus cases at 10 sites. Funding by the AES/EFA infrastructure award ends in December 2014. The current current grant application aims to obtain support that allows us to continue our efforts.
http://www.epilepsyfoundation.org/research/research-infrastructure-grant.cfm
http://www.aesnet.org/research/aes-sponsored-grant/research-infrastructure-awards/research-infrastructure-awards

​5. Title: Pediatric Status Epilepticus Research Group (PI Loddenkemper)
Funding Agency: The Pediatric Epilepsy Research Foundation (PERF)
Dates: 01/01/2016-12/31/2017 (current funding)
The goal of this project is to collect prospective data to determine diagnostic and therapeutic biomarkers in patients with both status epilepticus and refractory status epileticus. Data collection lead to enrollment of 261 refractory status epilepticus cases at 10 sites. Funding by the PERF award ends in December 2017. The current grant application aims to obtain support that allows us to continue our efforts.
http://pediatricepilepsyresearchfoundation.org/grants​

9. Jackson, M. Sánchez Fernández, I. Abend, N. Arya, R. Brenton, J. N. Carpenter, J. Chapman, K. Gaillard, W.D. Glauser, T. Goldstein, J. Goodkin, H. Helseth, A. Mikati, M. Peariso, K.  Tasker, R. Topjian, A. Wainwright, M. Wilfong, A. Williams, K. Loddenkemper, T. Clinical Characteristics and Outcomes of Status Epilepticus in Patients With and Without a Prior Diagnosis of Epilepsy. Poster presentation at the American Epilepsy Society Meeting 2015.


Marina Gaínza-Lein received the First Place for the prestigious “Ruth and William Silen, M.D. Award”  for her poster presentation on April 3rd, 2016 at the New England Science Symposium, sponsored by Harvard Medical School Office for Diversity Inclusion and Community Partnership and Biomedical Science Careers Program.

Poster: Status Epilepticus in Children: Relationship between Pre-hospital Treatment and Outcome


Category: Public Health, Epidemiology or Biostatistics, Bioinformatics, Physics, Chemistry, or Engineering and Clinical or Social Science, including Translational Research.

Grants

13.  Tchapyjnikov D, Feinstein L, Gaínza Lein M, Abend NS, Arya R, Brenton JN, Carpenter JL, Chapman K, Gaillard WD, Glauser T, Goldstein J, Goodkin HP, Helseth A, Jackson M, Peariso K, Sánchez Fernández I, Tasker RC, Topjian A, Wainwright M, Wilfong A, Williams K, Loddenkemper T, Mikati MA, And the Pediatric Status Epilepticus Research Group (pSERG). Under-Dosing of Lorazepam as a First-Line Anti-Epileptic Drug (AED) is Associated with Increased Seizure Duration in Pediatric Refractory Status Epilepticus. Poster presentation at the American Epilepsy Society Meeting, Houston, 2016. 

7. Loddenkemper, T. Sánchez Fernández, I. Jackson, M. Abend, N. Arya, R. Brenton, J. N. Carpenter, J. Chapman, K. Gaillard, W.D. Glauser, T. Goldstein, J. Goodkin, H. Helseth, A. Mikati, M. Peariso, K.  Tasker, R. Topjian, A. Wainwright, M. Wilfong, A. Williams, K. Factors Associated with Status Epilepticus Duration in Children. Poster presentation at the American Epilepsy Society Meeting 2015.


16. Sculier, Claudine; Gaínza-Lein, Marina; Gaspard, Nicolas; Sánchez Fernández, Iván; Abend, Nicholas S.; Anderson, Ann; Arya, Ravindra; Brenton, J. Nicholas; Carpenter, Jessica L.; Chapman, Kevin E.; Gaillard, William; Glauser, Tracy A.; Goldstein, Joshua L.; Goodkin, Howard P.; Mikati, Mohamad A.; Nayak, Anuranjita; Peariso, Katrina; Riviello, James J.;  Tasker, Robert C.; Tchapyjnikov, Dmitry; Topjian, Alexis A.; Wainwright, Mark S.; Wilfong, Angus; Williams, Korwyn;  Loddenkemper, Tobias, on behalf of Pediatric Status Epilepticus Research Group (pSERG). Children with New-Onset Refractory Status Epilepticus from a Multicenter US Registry. Abstract accepted to the European Paediatric Neurology Society, Lyon, France, 2017.

6. Loddenkemper T, Sanchez Fernandez I, Abend N, Arya R, Basu R, Brenton N, Carpenter J, Chapman K, Condie J, Dean N, Gaillard W, Glauser T, Goldstein J, Goodkin H, Hani A, Jackson M, Kebede T, Klehm J, Mikati M, Peariso K, Sacco M, Schmidt K, Topjian A, Turner D, Wilfong A, Williams K, Wainwright M, Tasker R. Continuous Infusions in Refractory Convulsive Status Epilepticus. Results from the Pediatric Status Epilepticus Research Group (pSERG). Platform presentation Dec 8, 2014 at the American Epilepsy Society Meeting, Seattle, WA. (Epilepsy Currents, 2014, in press).


3. Sánchez Fernández I, Abend N, Agadi S, An S, Arya R, Carpenter J, Chapman K, Gaillard W, Glauser T, Goodkin H,  Mikati M, Peariso K, Ramgopal S, Ream M, Loddenkemper T. Clinical characteristics and treatment strategies in refractory convulsive status epilepticus in children: results from the Pediatric Status Epilepticus Research Group (pSERG). Poster presentation at the 65th American Academy of Neurology. Neurology. 2013;80(Meeting Abstracts 1):P03.012.


10. Gaínza Lein, Marina; Sánchez Fernández, Iván; Jackson, Michele; Abend, Nicholas, Arya, Ravindra; Brenton, J. Nicholas; Carpenter, Jessica L.; Chapman, Kevin; Gaillard, William D.; Glauser, Tracy; Goldstein, Joshua; Goodkin, Howard P.; Helseth, Ashley; Kapur, Kush; Mikati, Mohamad; Peariso, Katrina; Tasker, Robert; Topjian, Alexis; Wainwright, Mark; Wilfong, Angus; Williams, Korwyn; Loddenkemper, Tobias; And the Pediatric Status Epilepticus Research Group (pSERG): Status epilepticus in children: relationship between pre-hospital treatment and outcome. Poster presentation at the American Academy of Neurology Meeting 2016.​​

 8. Chapman, K. Goodkin, H. Tasker, R. Sanchez Fernández, I. Topjian, A. Wilfong, A. Helseth, A. Carpenter, J. Goldstein, J. Peariso, K. Williams, K. Wainwright, M. Jackson, M. Mikati, M. Abend, N. Brenton, J. N. Arya, R. Glauser, T. Gaillard, W. D. Loddenkemper, T. Continuous Intravenous Therapy Versus Intermittent Bolus Therapy for Pediatric Refractory Status Epilepticus (RSE). Poster presentation at the American Epilepsy Society Meeting 2015.